Assessment of the antifungal susceptibility profile and virulence factors of non-albicans candida species obtained from the infection of the bloodstream

Background: Earlier the fungal infection spectrum was considered to be only restricted mucocutaneous and cutaneous tissues. However, this consideration has now changed. The threatening rise in incidence of invasive mycosis is seen recently. Despite advancements diagnostic therapeutic modalities, high mortality rates are linked mycosis. most common cause bloodstream infections Candida spp. Among candida genus, pathogenic species C. Albicans, recent literature data shown emergence treatment-resistant, relatively uncommon, unusual nonalbicans (NAC) Aim: present study conducted assess antifungal susceptibility profile virulence factors non-Albicans obtained from bloodstream. Material methods: included blood culture isolates which were identified level using standard mycological protocol. This NAC screened for production including biofilm formation, hemolysin, extracellular hydrolytic enzymes. Ezy MIC strip used assessing these isolates. Results: 100% (n=1) rugosa showed hemolysin production. In gulliermondii, 50% subject phospholipase formation each.